منابع مشابه
Gelatin tannate for treating acute gastroenteritis
In their review of gelatin tannate (GT) Ruszczyński et al [1] extensively explain tannic acid (TA) activity and they may give the impression that TA is responsible for the mechanism of action of GT and also responsible for the possible adverse effects of the product. Various in vivo studies have demonstrated that GT is a stable complex not dissociated in the small intestine. Therefore any refer...
متن کاملGelatin tannate for treating acute gastroenteritis: a systematic review
Gelatin tannate (GT) is a complex of tannic acid, which possesses astringent, antibacterial, and anti-inflammatory properties, and a protective gelatin. It is increasingly being marketed as an antidiarrheal drug. Our aim was to review data on the effectiveness of GT in treating acute gastroenteritis (AGE) in children and adults. The MEDLINE, EMBASE, and the Cochrane Library databases were searc...
متن کاملCharacterization of Hydrochloride and Tannate Salts of Diphenhydramine
Proper characterization is an important aspect of any dosage form design. The objective of this work was to characterize tannate salt and hydrochloride salt of diphenhydramine. As a part of characterization studies, Differential scanning calorimetry was used to investigate thermal effects and nature of salts, supported by X-ray powder diffraction. Scanning electron microphotographs was used to ...
متن کاملGelatine Tannate for the Treatment of Acute Diarrhoea in Adults
Gelatine tannate has been recently licensed as a medical device for the treatment of acute diarrhoea. Gelatine tannate is thought to act locally on the gut wall by forming a protective protein-based film and allowing the precipitation of pro-inflammatory mucoproteins from the intestinal mucus responsible for local inflammation, and subsequently eliminated through the faeces. In order to assess ...
متن کاملEvaluation of Gelatin Tannate Against Symptoms of Acute Diarrhea in Pediatric Patients
BACKGROUND Acute diarrhea is the second most common cause of morbidity and mortality worldwide, especially in children aged ≤3 years. Some drugs (e.g., the mucoprotector gelatin tannate) plus a reduced osmolality oral rehydration solution (ORS) may effectively reduce symptom duration and severity. The current trial was therefore designed to assess the efficacy and safety of gelatin tannate in p...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 1910
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja01928a028